Gene
myo7ab
- ID
- ZDB-GENE-091110-4
- Name
- myosin VIIAb
- Symbol
- myo7ab Nomenclature History
- Previous Names
-
- si:dkey-163i6.5
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Predicted to localize to myosin complex. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Usher syndrome (multiple); auditory system disease (multiple); and congenital nystagmus. Orthologous to human MYO7A (myosin VIIA).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal dominant nonsyndromic deafness 11 | Alliance | Deafness, autosomal dominant 11 | 601317 |
autosomal recessive nonsyndromic deafness 2 | Alliance | Deafness, autosomal recessive 2 | 600060 |
Usher syndrome type 1 | Alliance | Usher syndrome, type 1B | 276900 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein | Length |
---|---|
UniProtKB:A0A8M9PYX7
|
2177 |
UniProtKB:A0A8M1QV12
|
2191 |
UniProtKB:A0A8M3AWW6
|
2177 |
UniProtKB:A0A8M3AM80
|
2204 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
myo7ab-202
(1)
|
6500 nt |
Interactions and Pathways
No data available
Plasmids
No data available