Gene

stxbp5b

ID

ZDB-GENE-090821-5

Name

syntaxin binding protein 5b (tomosyn)

Symbol

stxbp5b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have several functions, including GTPase activator activity; Rab GTPase binding activity; and syntaxin binding activity. Predicted to be involved in regulation of exocytosis and regulation of protein secretion. Predicted to localize to SNARE complex and plasma membrane. Orthologous to human STXBP5 (syntaxin binding protein 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stxbp5b Human Ortholog

No data available

Associated With stxbp5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013577	Lethal giant larvae homologue 2
Domain	IPR013905	Lethal giant larvae (Lgl)-like, C-terminal domain
Domain	IPR042855	v-SNARE, coiled-coil homology domain
Family	IPR000664	Lethal(2) giant larvae protein
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Lethal(2) giant larvae protein	Lethal giant larvae homologue 2	Lethal giant larvae (Lgl)-like, C-terminal domain	v-SNARE, coiled-coil homology domain	WD40 repeat	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M3AR50 InterPro	1136
UniProtKB:A0A8M3AU07 InterPro	1151
UniProtKB:A0A8M9PCI5 InterPro	142
UniProtKB:A0A8M3B255 InterPro	1186
UniProtKB:A0A8M2B5G8 InterPro	1108
UniProtKB:A0A8M3AJL2 InterPro	1158
UniProtKB:E7F0C0 InterPro	1123

Transcripts

Genome Browsers

NCBI

No data available

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations