Gene
htr1ab
- ID
- ZDB-GENE-090409-2
- Name
- 5-hydroxytryptamine (serotonin) receptor 1A b
- Symbol
- htr1ab Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled serotonin receptor activity and serotonin binding activity. Involved in spinal cord motor neuron differentiation. Predicted to localize to dendrite and integral component of plasma membrane. Human ortholog(s) of this gene implicated in anxiety disorder; mental depression; and panic disorder. Is expressed in brain; pharynx; retina; and spinal cord. Orthologous to human HTR1A (5-hydroxytryptamine receptor 1A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Barreiro-Iglesias et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| vesicoureteral reflux | Alliance | Periodic fever, menstrual cycle dependent | 614674 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 5-hydroxytryptamine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|
|
UniProtKB:C0ITL9
|
403 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
htr1ab-202
(1)
|
Havana | 1438 nt |
Interactions and Pathways
No data available
Plasmids
No data available