Gene

ghsrb

ID
ZDB-GENE-090327-1
Name
growth hormone secretagogue receptor b
Symbol
ghsrb Nomenclature History
Previous Names
  • GHS-R2a (1)
  • si:dkey-83f6.2
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have growth hormone secretagogue receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Localizes to perinuclear region of cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in obesity. Is expressed in several structures, including brain; brainstem and spinal white matter; immune system; intestine; and liver. Orthologous to human GHSR (growth hormone secretagogue receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ghsrb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Growth hormone deficiency, isolated partial 615925
Associated With ghsrb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR003905 Growth hormone secretagogue receptor/motilin receptor
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Growth hormone secretagogue receptor/motilin receptor
UniProtKB:E7EZL2 365
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations