Gene

cgasa

ID
ZDB-GENE-090313-23
Name
cyclic GMP-AMP synthase a
Symbol
cgasa Nomenclature History
Previous Names
  • cgas (1)
  • mb21d1
  • si:ch211-12a5.1
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have chromatin binding activity; cyclic-GMP-AMP synthase activity; and double-stranded DNA binding activity. Predicted to be involved in several processes, including cellular response to exogenous dsRNA; positive regulation of intracellular signal transduction; and regulation of defense response. Predicted to localize to cytosol; nucleus; and site of double-strand break. Orthologous to human CGAS (cyclic GMP-AMP synthase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Ge et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cgasa Human Ortholog
No data available
Associated With cgasa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR046903 Mab-21-like, nucleotidyltransferase domain
Domain IPR046906 Mab-21-like, HhH/H2TH-like domain
Domain Details Per Protein
Protein Length Mab-21-like, HhH/H2TH-like domain Mab-21-like, nucleotidyltransferase domain
UniProtKB:F1QCP4 592
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA mb21d1-202 (1) Havana 810 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations