Gene

cnga1a

ID

ZDB-GENE-090312-66

Name

cyclic nucleotide gated channel subunit alpha 1a

Symbol

cnga1a Nomenclature History

Previous Names

si:dkey-22i16.2 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transmembrane transport and visual perception. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 49. Orthologous to human CNGA1 (cyclic nucleotide gated channel subunit alpha 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cnga1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
retinitis pigmentosa 49	Alliance	Retinitis pigmentosa 49	613756

Associated With cnga1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018488	Cyclic nucleotide-binding, conserved site
Domain	IPR000595	Cyclic nucleotide-binding domain
Domain	IPR005821	Ion transport domain
Domain	IPR032406	Cyclic nucleotide-gated channel, C-terminal leucine zipper domain
Family	IPR050866	Cyclic nucleotide-gated cation channel
Homologous_superfamily	IPR014710	RmlC-like jelly roll fold
Homologous_superfamily	IPR018490	Cyclic nucleotide-binding domain superfamily