Gene

atp11a

ID

ZDB-GENE-090311-52

Name

ATPase phospholipid transporting 11A

Symbol

atp11a Nomenclature History

Previous Names

si:dkey-251i8.1

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have ATPase-coupled intramembrane lipid transporter activity. Predicted to be involved in phospholipid translocation. Predicted to localize to several cellular components, including endoplasmic reticulum; recycling endosome; and trans-Golgi network. Orthologous to human ATP11A (ATPase phospholipid transporting 11A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Hawkey-Noble et al., 2020

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atp11a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hypomyelinating leukodystrophy 24	Alliance	?Leukodystrophy, hypomyelinating, 24	619851
		Deafness, autosomal dominant 84	619810
		?Auditory neuropathy, autosomal dominant 2	620384

Associated With atp11a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR032630	P-type ATPase, C-terminal
Domain	IPR032631	P-type ATPase, N-terminal
Domain	IPR044492	P-type ATPase, haloacid dehalogenase domain
Family	IPR001757	P-type ATPase
Family	IPR006539	P-type ATPase, subfamily IV
Homologous_superfamily	IPR008250	P-type ATPase, A domain superfamily
Homologous_superfamily	IPR023214	HAD superfamily
Homologous_superfamily	IPR023298	P-type ATPase, transmembrane domain superfamily
Homologous_superfamily	IPR023299	P-type ATPase, cytoplasmic domain N
Homologous_superfamily	IPR036412	HAD-like superfamily
PTM	IPR018303	P-type ATPase, phosphorylation site

Domain Details Per Protein

Protein	Length	HAD-like superfamily	HAD superfamily	P-type ATPase	P-type ATPase, A domain superfamily	P-type ATPase, C-terminal	P-type ATPase, cytoplasmic domain N	P-type ATPase, haloacid dehalogenase domain	P-type ATPase, N-terminal	P-type ATPase, phosphorylation site	P-type ATPase, subfamily IV	P-type ATPase, transmembrane domain superfamily
UniProtKB:A0A8M2BIA1 InterPro	1212
UniProtKB:A0A8M9Q0D9 InterPro	1204
UniProtKB:F8W2B0 InterPro	1177
UniProtKB:A0A8M2BIB5 InterPro	1145
UniProtKB:A0A8M9Q0F1 InterPro	1145
UniProtKB:A0A8M2BI82 InterPro	1177
UniProtKB:A0A8M9QFY8 InterPro	1149
UniProtKB:A0A8N7TDX5 InterPro	1137
UniProtKB:A0A8M9QFZ2 InterPro	1137
UniProtKB:A0A8M9Q0D3 InterPro	1212
UniProtKB:A0A8M2BIQ7 InterPro	1204

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	atp11a-203 (1) Ensembl	Havana	3375 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	atp11a-204 (1) Ensembl	Havana	10460 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	atp11a-002 (1) Ensembl	Havana	462 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations