tgfbr2l

ID

ZDB-GENE-081105-143

Name

transforming growth factor beta receptor-like

Symbol

tgfbr2l Nomenclature History

Previous Names

si:dkey-101k6.5

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable several functions, including activin binding activity; transforming growth factor beta binding activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in several processes, including activin receptor signaling pathway; cellular response to growth factor stimulus; and heart development. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane raft. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tgfbr2l Human Ortholog

No data available

Associated With tgfbr2l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR015013	Transforming growth factor beta receptor 2 ectodomain
Family	IPR000333	Ser/Thr protein kinase, TGFB receptor
Family	IPR017194	Transforming growth factor-beta receptor, type II
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR045860	Snake toxin-like superfamily