ZFIN is now using GRCz12tu for Genomic Data
Gene
rnf180a
- ID
- ZDB-GENE-081104-393
- Name
- ring finger protein 180a
- Symbol
- rnf180a Nomenclature History
- Previous Names
-
- si:dkey-250l23.4
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in norepinephrine metabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and serotonin metabolic process. Predicted to be located in nuclear envelope. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human RNF180 (ring finger protein 180).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR018957 | Zinc finger, C3HC4 RING-type |
| Domain | IPR045790 | E3 ubiquitin-protein ligase RNF180, C-terminal domain |
| Family | IPR033263 | E3 ubiquitin-protein ligase RNF180 |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Additional Resources | Length | E3 ubiquitin-protein ligase RNF180 | E3 ubiquitin-protein ligase RNF180, C-terminal domain | Zinc finger, C3HC4 RING-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8N7UT38 | InterPro | 365 | ||||||
| UniProtKB:A0AB32TTZ9 | InterPro | 366 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-250l23.4-001
(1)
|
Ensembl | 1,090 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers