ZFIN is now using GRCz12tu for Genomic Data
Gene
pex6
- ID
- ZDB-GENE-081104-252
- Name
- peroxisomal biogenesis factor 6
- Symbol
- pex6 Nomenclature History
- Previous Names
-
- si:ch73-197b13.2
- si:ch73-197b13.3
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Unknown
- Description
- Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in anatomical structure morphogenesis. Predicted to be located in cytosol; peroxisomal membrane; and photoreceptor outer segment. Human ortholog(s) of this gene implicated in Heimler syndrome 2; Peroxisome biogenesis disorder 4B; and peroxisome biogenesis disorder 4A. Orthologous to human PEX6 (peroxisomal biogenesis factor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Heimler syndrome 2 | Alliance | Heimler syndrome 2 | 616617 |
| peroxisome biogenesis disorder 4A | Alliance | Peroxisome biogenesis disorder 4A (Zellweger) | 614862 |
| peroxisome biogenesis disorder 4B | Alliance | Peroxisome biogenesis disorder 4B | 614863 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003960 | ATPase, AAA-type, conserved site |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR041569 | AAA ATPase, AAA+ lid domain |
| Domain | IPR047533 | Peroxisomal biogenesis factor 6, second ATPase domain |
| Family | IPR050168 | AAA ATPase domain-containing protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA ATPase, AAA+ lid domain | AAA+ ATPase domain | AAA ATPase domain-containing protein | ATPase, AAA-type, conserved site | ATPase, AAA-type, core | Peroxisomal biogenesis factor 6, second ATPase domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QMB0 | InterPro | 1071 | |||||||
| UniProtKB:A0A8M9PSM5 | InterPro | 564 | |||||||
| UniProtKB:A0A8M9P4U9 | InterPro | 507 | |||||||
| UniProtKB:A0AC58IHP3 | InterPro | 507 | |||||||
| UniProtKB:A0ACD6B693 | InterPro | 1071 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers