Gene
phc1
- ID
- ZDB-GENE-081022-39
- Name
- polyhomeotic homolog 1
- Symbol
- phc1 Nomenclature History
- Previous Names
-
- zgc:193796
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have zinc ion binding activity. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 11. Orthologous to human PHC1 (polyhomeotic homolog 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Espanola et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal recessive microcephaly 11 | Alliance | ?Microcephaly 11, primary, autosomal recessive | 615414 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001660 | Sterile alpha motif domain |
| Domain | IPR012313 | Zinc finger, FCS-type |
| Family | IPR050548 | Polycomb group and chromatin remodeling factors |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
| Homologous_superfamily | IPR038603 | FCS-type zinc finger superfamily |
Domain Details Per Protein
| Protein | Length | FCS-type zinc finger superfamily | Polycomb group and chromatin remodeling factors | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily | Zinc finger, FCS-type |
|---|---|---|---|---|---|---|
|
UniProtKB:E7F4T8
|
901 | |||||
|
UniProtKB:Q7T2Y0
|
827 | |||||
|
UniProtKB:A0A8M2B579
|
889 |
Interactions and Pathways
No data available
Plasmids
No data available