ZFIN is now using GRCz12tu for Genomic Data
Gene
top6bl
- ID
- ZDB-GENE-081022-196
- Name
- TOP6B like initiator of meiotic double strand breaks
- Symbol
- top6bl Nomenclature History
- Previous Names
-
- zgc:195212 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to act upstream of or within meiotic DNA double-strand break formation. Human ortholog(s) of this gene implicated in gestational trophoblastic neoplasm. Orthologous to human TOP6BL (TOP6B like initiator of meiotic double strand breaks).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Hydatidiform mole, recurrent, 4 | 618432 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR028040 | Type 2 DNA topoisomerase 6 subunit B-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | Type 2 DNA topoisomerase 6 subunit B-like |
|---|---|---|---|
| UniProtKB:B3DIP6 | InterPro | 450 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:195212-201
(1)
|
Ensembl | 1,386 nt | ||
| mRNA |
zgc:195212-202
(1)
|
Ensembl | 1,864 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers