Gene

pbrm1

ID

ZDB-GENE-080926-4

Name

polybromo 1

Symbol

pbrm1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have DNA binding activity and chromatin binding activity. Predicted to be involved in chromatin remodeling. Predicted to localize to RSC-type complex. Is expressed in somite. Orthologous to human PBRM1 (polybromo 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Armant et al., 2013

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pbrm1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
nonpapillary renal cell carcinoma	Alliance	?Renal cell carcinoma, clear cell	144700

Associated With pbrm1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018359	Bromodomain, conserved site
Domain	IPR001025	Bromo adjacent homology (BAH) domain
Domain	IPR001487	Bromodomain
Domain	IPR009071	High mobility group box domain
Domain	IPR037968	Protein polybromo-1, Bromodomain 5
Family	IPR037382	Remodelling complex subunit Rsc/polybromo
Homologous_superfamily	IPR036427	Bromodomain-like superfamily
Homologous_superfamily	IPR036910	High mobility group box domain superfamily
Homologous_superfamily	IPR043151	Bromo adjacent homology (BAH) domain superfamily

Domain Details Per Protein

Protein	Length	Bromo adjacent homology (BAH) domain	Bromo adjacent homology (BAH) domain superfamily	Bromodomain	Bromodomain, conserved site	Bromodomain-like superfamily	High mobility group box domain	High mobility group box domain superfamily	Protein polybromo-1, Bromodomain 5	Remodelling complex subunit Rsc/polybromo
UniProtKB:E7F8D8 InterPro	1627
UniProtKB:A0A8M3B6P7 InterPro	1559
UniProtKB:A0A8M9QLS6 InterPro	1582

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pbrm1-201 (1) Ensembl	Havana	5413 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pbrm1-202 (1) Ensembl	Havana	5756 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations