Gene
igdcc3
- ID
- ZDB-GENE-080303-24
- Name
- immunoglobulin superfamily, DCC subclass, member 3
- Symbol
- igdcc3 Nomenclature History
- Previous Names
-
- sc:d837
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Is expressed in several structures, including nervous system; neural plate; notochord; otic vesicle; and presumptive diencephalon. Orthologous to human IGDCC3 (immunoglobulin superfamily DCC subclass member 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from Thisse et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d837 (23 images)
- cssl:d0665 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la025965Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la025966Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la029329Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa34099 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa34100 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
igdcc3-201
(1)
|
Ensembl | 9,575 nt | ||
| ncRNA |
igdcc3-002
(1)
|
Ensembl | 1,560 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-174E24 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-249N13 | ZFIN Curated Data | |
| Encodes | EST | cssl:d0665 | Thisse et al., 2008 | |
| Encodes | cDNA | cssl:d837 | Bushell et al., 2007 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001098244 (1) | 1561 nt | ||
| Genomic | GenBank:CR318636 (1) | 197182 nt | ||
| Polypeptide | RefSeq:XP_003199017 (1) | 773 aa |
- Taylor, R., Hamid, F., Fielding, T., Gordon, P.M., Maloney, M., Makeyev, E.V., Houart, C. (2022) Prematurely terminated intron-retaining mRNAs invade axons in SFPQ null-driven neurodegeneration and are a hallmark of ALS. Nature communications. 13:69946994
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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