Gene

pdzrn3b

ID

ZDB-GENE-071022-4

Name

PDZ domain containing RING finger 3b

Symbol

pdzrn3b Nomenclature History

Previous Names

pdzrn3

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have ubiquitin protein ligase activity. Predicted to be involved in neuromuscular junction development and protein ubiquitination. Predicted to localize to cell junction; cytoplasm; and synapse. Is expressed in several structures, including hindbrain neural plate; nervous system; notochord; optic vesicle; and presumptive neural retina. Orthologous to human PDZRN3 (PDZ domain containing ring finger 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pdzrn3b Human Ortholog

No data available

Associated With pdzrn3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Domain	IPR001478	PDZ domain
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR003613	U-box domain
Family	IPR051971	E3 ubiquitin-protein ligase PDZ domain-containing protein
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	E3 ubiquitin-protein ligase PDZ domain-containing protein	PDZ domain	PDZ superfamily	U-box domain	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type	Zinc finger, RING-type, conserved site
UniProtKB:E7FDW2 InterPro	1053
UniProtKB:A0A8M2BDD2 InterPro	772

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pdzrn3b-201 (1) Ensembl	Ensembl	4,320 nt	Select Tool ZFIN BLAST
mRNA	pdzrn3b-203 (1) Ensembl	Ensembl	5,753 nt	Select Tool ZFIN BLAST
mRNA	pdzrn3b-204 (1) Ensembl	Ensembl	5,723 nt	Select Tool ZFIN BLAST
ncRNA	pdzrn3b-002 (1) Ensembl	Ensembl	555 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations