Gene

dgkh

ID

ZDB-GENE-070912-328

Name

diacylglycerol kinase, eta

Symbol

dgkh Nomenclature History

Previous Names

si:ch211-93a19.1

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have diacylglycerol kinase activity. Predicted to be involved in diacylglycerol metabolic process; intracellular signal transduction; and lipid phosphorylation. Is expressed in Purkinje cell. Orthologous to human DGKH (diacylglycerol kinase eta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Takeuchi et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dgkh Human Ortholog

No data available

Associated With dgkh Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000756	Diacylglycerol kinase, accessory domain
Domain	IPR001206	Diacylglycerol kinase, catalytic domain
Domain	IPR001660	Sterile alpha motif domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain	IPR047480	Diacylglycerol kinase eta, second protein kinase C conserved region 1
Family	IPR037607	Diacylglycerol kinase
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily
Homologous_superfamily	IPR016064	NAD kinase/diacylglycerol kinase-like domain superfamily
Homologous_superfamily	IPR017438	Inorganic polyphosphate/ATP-NAD kinase, N-terminal
Homologous_superfamily	IPR046349	C1-like domain superfamily

Domain Details Per Protein

Protein	Length	C1-like domain superfamily	Diacylglycerol kinase	Diacylglycerol kinase, accessory domain	Diacylglycerol kinase, catalytic domain	Diacylglycerol kinase eta, second protein kinase C conserved region 1	Inorganic polyphosphate/ATP-NAD kinase, N-terminal	NAD kinase/diacylglycerol kinase-like domain superfamily	PH-like domain superfamily	Pleckstrin homology domain	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Sterile alpha motif domain	Sterile alpha motif/pointed domain superfamily
UniProtKB:A0A8M9PSF8 InterPro	197
UniProtKB:A0A8M2BFF5 InterPro	1257
UniProtKB:A0A8M9PSN5 InterPro	1107
UniProtKB:A0A8M3B2L0 InterPro	1306
UniProtKB:A0A8M3AVY2 InterPro	1251
UniProtKB:A0A8M9PA12 InterPro	246
UniProtKB:A0A8M9QFV5 InterPro	1329
UniProtKB:A0A8M9PLC4 InterPro	224