Gene
adamts9
- ID
- ZDB-GENE-070814-6
- Name
- ADAM metallopeptidase with thrombospondin type 1 motif, 9
- Symbol
- adamts9 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have metalloendopeptidase activity. Involved in endocrine pancreas development and pancreas regeneration. Is expressed in several structures, including brain; digestive system; heart; pleuroperitoneal region; and thymus. Orthologous to human ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 11 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
scoliosis | adamts9stl316/stl316 | standard conditions | Gray et al., 2020 |
scoliosis | adamts9stl756/stl756 | standard conditions | Gray et al., 2020 |
scoliosis | adamts9stl336/stl336 | standard conditions | Gray et al., 2020 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001590 | Peptidase M12B, ADAM/reprolysin |
Domain | IPR002870 | Peptidase M12B, propeptide |
Domain | IPR010294 | ADAMTS/ADAMTS-like, Spacer 1 |
Domain | IPR041645 | ADAMTS, cysteine-rich domain 2 |
Domain | IPR045371 | ADAMTS/ADAMTS-like, cysteine-rich domain 3 |
Family | IPR013273 | ADAMTS/ADAMTS-like |
Family | IPR050439 | ADAMTS and ADAMTS-like |
Homologous_superfamily | IPR024079 | Metallopeptidase, catalytic domain superfamily |
Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
Domain Details Per Protein
Protein | Length | ADAMTS/ADAMTS-like | ADAMTS/ADAMTS-like, cysteine-rich domain 3 | ADAMTS/ADAMTS-like, Spacer 1 | ADAMTS and ADAMTS-like | ADAMTS, cysteine-rich domain 2 | Metallopeptidase, catalytic domain superfamily | Peptidase M12B, ADAM/reprolysin | Peptidase M12B, propeptide | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:G3G3K0
|
1643 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
adamts9-201
(1)
|
Ensembl | 10,402 nt | ||
mRNA |
adamts9-202
(1)
|
Ensembl | 4,386 nt |
Interactions and Pathways
No data available
Plasmids
No data available