Gene
hscb
- ID
- ZDB-GENE-070705-97
- Name
- HscB mitochondrial iron-sulfur cluster cochaperone
- Symbol
- hscb Nomenclature History
- Previous Names
-
- si:ch211-207k7.4
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have ATPase activator activity and chaperone binding activity. Predicted to be involved in [2Fe-2S] cluster assembly. Predicted to localize to mitochondrion. Orthologous to human HSCB (HscB mitochondrial iron-sulfur cluster cochaperone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Crispin et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Crispin et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| sideroblastic anemia 5 | Alliance | ?Anemia, sideroblastic, 5 | 619523 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| sideroblastic anemia | WT + MO1-hscb | standard conditions | Crispin et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Chaperone J-domain superfamily | Co-chaperone Hsc20 | Co-chaperone HscB, C-terminal oligomerisation domain | DnaJ domain | HscB, C-terminal domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:B0V1J6
|
267 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-207k7.4-201
(1)
|
Ensembl | 963 nt |
Interactions and Pathways
No data available
Plasmids
No data available