ZFIN is now using GRCz12tu for Genomic Data
Gene
kif5ba
- ID
- ZDB-GENE-070629-2
- Name
- kinesin family member 5B, a
- Symbol
- kif5ba Nomenclature History
- Previous Names
-
- si:ch211-159p3.5
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Acts upstream of or within germ cell development; skeletal muscle tissue development; and skeletal system development. Predicted to be located in axon cytoplasm; cytoskeleton; and dendrite cytoplasm. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm and microtubule. Is expressed in several structures, including central nervous system; digestive system; eye; pleuroperitoneal region; and trigeminal placode. Orthologous to human KIF5B (kinesin family member 5B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| kyphomelic dysplasia, Itai-Ikegawa type | Alliance | Kyphomelic dysplasia, Itai-Ikegawa type | 621644 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019821 | Kinesin motor domain, conserved site |
| Domain | IPR001752 | Kinesin motor domain |
| Domain | IPR059182 | Kinesin heavy chain, C-terminal domain |
| Family | IPR027640 | Kinesin-like protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Kinesin heavy chain, C-terminal domain | Kinesin-like protein | Kinesin motor domain | Kinesin motor domain, conserved site | Kinesin motor domain superfamily | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BJ79 | InterPro | 969 | ||||||
| UniProtKB:A0A0R4IRM1 | InterPro | 959 | ||||||
| UniProtKB:F1R5M2 | InterPro | 968 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kif5ba-201
(1)
|
Ensembl | 3,283 nt | ||
| mRNA |
kif5ba-202
(1)
|
Ensembl | 2,745 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers