ZFIN is now using GRCz12tu for Genomic Data
Gene
slc9a6a
- ID
- ZDB-GENE-070424-104
- Name
- solute carrier family 9 member A6a
- Symbol
- slc9a6a Nomenclature History
- Previous Names
-
- fv47b07
- wu:fv47b07
- zgc:163055
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable sodium:proton antiporter activity. Predicted to be involved in proton transmembrane transport; regulation of pH; and sodium ion transmembrane transport. Predicted to be located in plasma membrane and recycling endosome membrane. Human ortholog(s) of this gene implicated in Christianson syndrome and Parkinsonism. Orthologous to human SLC9A6 (solute carrier family 9 member A6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Christianson syndrome | Alliance | Intellectual developmental disorder, X-linked syndromic, Christianson type | 300243 |
| X-linked female-restricted neurodegenerative disorder with Parkinsonism and cognitive impairment | Alliance | Neurodegenerative disorder, X-linked, female-restricted, with parkinsonism and cognitive impairment | 301142 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cation/H+ exchanger, CPA1 family | Cation/H+ exchanger, transmembrane domain | Na+/H+ exchanger | Sodium/hydrogen exchanger 6/7/9 |
|---|---|---|---|---|---|---|
| UniProtKB:F1QSJ6 | InterPro | 697 | ||||
| UniProtKB:A0A8M3AP93 | InterPro | 732 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc9a6a-201
(1)
|
Ensembl | 8,162 nt | ||
| ncRNA |
slc9a6a-002
(1)
|
Ensembl | 666 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers