Gene

tgfbrap1

ID

ZDB-GENE-070410-66

Name

transforming growth factor, beta receptor associated protein 1

Symbol

tgfbrap1 Nomenclature History

Previous Names

zgc:162302

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have SMAD binding activity. Predicted to be involved in signal transduction and vesicle-mediated transport. Predicted to localize to early endosome. Orthologous to human TGFBRAP1 (transforming growth factor beta receptor associated protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Zhang et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tgfbrap1 Human Ortholog

No data available

Associated With tgfbrap1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001180	Citron homology (CNH) domain
Domain	IPR019452	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1
Domain	IPR019453	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2
Family	IPR032914	Vam6/VPS39/TRAP1 family
Repeat	IPR000547	Clathrin, heavy chain/VPS, 7-fold repeat

Domain Details Per Protein

Protein	Length	Citron homology (CNH) domain	Clathrin, heavy chain/VPS, 7-fold repeat	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1	Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2	Vam6/VPS39/TRAP1 family
UniProtKB:A4IG72 InterPro	863
UniProtKB:A0A8M3B3B0 InterPro	511

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tgfbrap1-201 (1) Ensembl	Havana	2951 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	tgfbrap1-002 (1) Ensembl	Havana	834 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	tgfbrap1-003 (1) Ensembl	Havana	653 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations