Gene

dnajc10

ID

ZDB-GENE-070327-1

Name

DnaJ (Hsp40) homolog, subfamily C, member 10

Symbol

dnajc10 Nomenclature History

Previous Names

zgc:162218

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable misfolded protein binding activity; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; and protein-disulfide reductase activity. Predicted to be involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum lumen. Orthologous to human DNAJC10 (DnaJ heat shock protein family (Hsp40) member C10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7161373 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dnajc10 Human Ortholog

No data available

Associated With dnajc10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017937	Thioredoxin, conserved site
Domain	IPR001623	DnaJ domain
Domain	IPR013766	Thioredoxin domain
Domain	IPR035673	ERdj5, first thioredoxin domain
Domain	IPR035674	ERdj5, C-terminal thioredoxin domain
Family	IPR052460	Endoplasmic reticulum disulfide reductase
Homologous_superfamily	IPR036249	Thioredoxin-like superfamily
Homologous_superfamily	IPR036869	Chaperone J-domain superfamily