Gene

sh2b1

ID
ZDB-GENE-070209-188
Name
SH2B adaptor protein 1
Symbol
sh2b1 Nomenclature History
Previous Names
  • zgc:158474
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in intracellular signal transduction. Predicted to localize to plasma membrane. Orthologous to human SH2B1 (SH2B adaptor protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sh2b1 Human Ortholog
No data available
Associated With sh2b1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR015012 Phenylalanine zipper
Domain IPR035057 SH2B1, SH2 domain
Family IPR030523 SH2B adapter protein
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR036290 Phenylalanine zipper superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length Phenylalanine zipper Phenylalanine zipper superfamily PH-like domain superfamily Pleckstrin homology domain SH2B1, SH2 domain SH2B adapter protein SH2 domain SH2 domain superfamily
UniProtKB:A2RUZ0 906
UniProtKB:A0A8M2BAY6 858
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sh2b1-201 (1) Ensembl 3,596 nt
mRNA sh2b1-202 (1) Ensembl 4,210 nt
mRNA sh2b1-203 (1) Ensembl 882 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations