ZFIN is now using GRCz12tu for Genomic Data
Gene
rbl2
- ID
- ZDB-GENE-061109-2
- Name
- retinoblastoma-like 2 (p130)
- Symbol
- rbl2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in regulation of cell cycle and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in neuromast. Human ortholog(s) of this gene implicated in Brunet-Wagner neurodevelopmental syndrome. Orthologous to human RBL2 (RB transcriptional corepressor like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Brunet-Wagner neurodevelopmental syndrome | Alliance | Brunet-Wagner neurodevelopmental syndrome | 619690 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002719 | Retinoblastoma-associated protein, B-box |
| Domain | IPR002720 | Retinoblastoma-associated protein, A-box |
| Domain | IPR013763 | Cyclin-like domain |
| Domain | IPR015030 | Retinoblastoma-associated protein, C-terminal |
| Domain | IPR024599 | Retinoblastoma-associated protein, N-terminal |
| Family | IPR028309 | Retinoblastoma protein family |
| Homologous_superfamily | IPR036915 | Cyclin-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cyclin-like domain | Cyclin-like superfamily | Retinoblastoma-associated protein, A-box | Retinoblastoma-associated protein, B-box | Retinoblastoma-associated protein, C-terminal | Retinoblastoma-associated protein, N-terminal | Retinoblastoma protein family |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BA88 | InterPro | 897 | |||||||
| UniProtKB:A0A8M3AZW2 | InterPro | 1078 | |||||||
| UniProtKB:E7FDM3 | InterPro | 1079 | |||||||
| UniProtKB:A0ACD6B5T3 | InterPro | 1079 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers