Gene

rfx3

ID
ZDB-GENE-061103-253
Name
regulatory factor X, 3 (influences HLA class II expression)
Symbol
rfx3 Nomenclature History
Previous Names
  • zgc:153245 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cilium-dependent cell motility; epithelial cilium movement involved in determination of left/right asymmetry; and regulation of insulin secretion. Predicted to localize to nucleus. Orthologous to human RFX3 (regulatory factor X3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rfx3 Human Ortholog
No data available
Associated With rfx3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003150 DNA-binding RFX-type winged-helix domain
Domain IPR007668 RFX1 transcription activation region
Family IPR039779 RFX-like DNA-binding protein
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length DNA-binding RFX-type winged-helix domain RFX1 transcription activation region RFX-like DNA-binding protein Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A8M9PTM1 740
UniProtKB:A0JMF8 765
UniProtKB:B2GSV8 765
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations