Gene

tpcn2

ID
ZDB-GENE-061103-202
Name
two pore segment channel 2
Symbol
tpcn2 Nomenclature History
Previous Names
  • fi42c05
  • im:7140344
  • wu:fi42c05
  • zgc:152898
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have NAADP-sensitive calcium-release channel activity and voltage-gated calcium channel activity. Involved in calcium-mediated signaling; regulation of myotome development; and skeletal myofibril assembly. Predicted to localize to lysosomal membrane. Is expressed in slow muscle cell. Orthologous to human TPCN2 (two pore segment channel 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tpcn2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Skin/hair/eye pigmentation 10, blond/brown hair] 612267
Associated With tpcn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Family IPR028798 Two pore channel protein 2
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length Ion transport domain Two pore channel protein 2 Voltage-dependent channel domain superfamily
UniProtKB:A0JMD4 774
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations