Gene

pkn2b

ID

ZDB-GENE-061013-393

Name

protein kinase N2b

Symbol

pkn2b Nomenclature History

Previous Names

zgc:153916

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to localize to several cellular components, including cleavage furrow; lamellipodium; and midbody. Orthologous to human PKN2 (protein kinase N2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pkn2b Human Ortholog

No data available

Associated With pkn2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000008	C2 domain
Domain	IPR000719	Protein kinase domain
Domain	IPR000961	AGC-kinase, C-terminal
Domain	IPR011072	HR1 rho-binding domain
Domain	IPR017892	Protein kinase, C-terminal
Domain	IPR037313	Serine/threonine-protein kinase N, first HR1 domain
Domain	IPR037784	Serine/threonine-protein kinase N, C2 domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR035892	C2 domain superfamily
Homologous_superfamily	IPR036274	HR1 repeat superfamily

Domain Details Per Protein

Protein	Length	AGC-kinase, C-terminal	C2 domain	C2 domain superfamily	HR1 repeat superfamily	HR1 rho-binding domain	Protein kinase, ATP binding site	Protein kinase, C-terminal	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site	Serine/threonine-protein kinase N, C2 domain	Serine/threonine-protein kinase N, first HR1 domain
UniProtKB:A7MBL8 InterPro	977
UniProtKB:A0A2R8RL78 InterPro	984
UniProtKB:Q08BD6 InterPro	339

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ottdart00000054614 (1) Ensembl	Havana	3950 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pkn2-204 (1) Ensembl	Havana	1937 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations