Gene
zgc:153031
- ID
- ZDB-GENE-060929-1190
- Name
- zgc:153031
- Symbol
- zgc:153031 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable NADP binding activity and dihydrofolate reductase activity. Predicted to be involved in dihydrofolate metabolic process; folic acid metabolic process; and tetrahydrofolate biosynthetic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Orthologous to human DHFR (dihydrofolate reductase) and DHFR2 (dihydrofolate reductase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Dihydrofolate reductase | Dihydrofolate reductase domain | Dihydrofolate reductase-like domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q1LWC6 | InterPro | 195 | |||
| UniProtKB:A0A8M9PFG2 | InterPro | 175 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:153031-201
(1)
|
Ensembl | 3,094 nt |
Interactions and Pathways
No data available
Plasmids
No data available