ZFIN is now using GRCz12tu for Genomic Data
Gene
lipt1
- ID
- ZDB-GENE-060929-112
- Name
- lipoyltransferase 1
- Symbol
- lipt1 Nomenclature History
- Previous Names
-
- fi89f05
- wu:fi89f05
- zgc:152851
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable lipoyltransferase activity. Predicted to be involved in protein lipoylation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in Leigh disease. Orthologous to human LIPT1 (lipoyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Lipoyltransferase 1 deficiency | 616299 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004143 | Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain |
| Family | IPR004562 | Lipoyltransferase/lipoate-protein ligase |
| Homologous_superfamily | IPR045864 | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) |
Domain Details Per Protein
| Protein | Additional Resources | Length | Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) | Lipoyltransferase/lipoate-protein ligase |
|---|---|---|---|---|---|
| UniProtKB:Q08CP2 | InterPro | 372 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers