Gene

tbcd

ID
ZDB-GENE-060823-1
Name
tubulin folding cofactor D
Symbol
tbcd Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity and beta-tubulin binding activity. Involved in brain development and retina layer formation. Predicted to localize to lateral plasma membrane. Orthologous to human TBCD (tubulin folding cofactor D).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Pode-Shakked et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tbcd Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
early onset progressive encephalopathy with brain atrophy and thin corpus callosum Alliance Encephalopathy, progressive, early-onset, with brain atrophy and thin corpus callosum 617193
Associated With tbcd Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR022577 Tubulin-specific chaperone D, C-terminal
Family IPR033162 Tubulin-folding cofactor D
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Armadillo-like helical Armadillo-type fold Tubulin-folding cofactor D Tubulin-specific chaperone D, C-terminal
UniProtKB:A0A0R4IXD9 1191
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations