Gene

pals1b

ID
ZDB-GENE-060531-2
Name
protein associated with LIN7 1, MAGUK p55 family member b
Symbol
pals1b Nomenclature History
Previous Names
  • im:7140055
  • mpp5b
  • ponli (1)
  • sb:eu974
  • si:ch211-105d18.1
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to be involved in bicellular tight junction assembly and establishment of epithelial cell polarity. Is expressed in eye; retinal cone cell; and retinal photoreceptor layer. Orthologous to human MPP5 (membrane palmitoylated protein 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pals1b Human Ortholog
No data available
Associated With pals1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020590 Guanylate kinase, conserved site
Domain IPR001452 SH3 domain
Domain IPR001478 PDZ domain
Domain IPR004172 L27 domain
Domain IPR008144 Guanylate kinase-like domain
Domain IPR008145 Guanylate kinase/L-type calcium channel beta subunit
Domain IPR014775 L27 domain, C-terminal
Domain IPR015145 L27-N
Domain IPR035601 MPP5, SH3 domain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Homologous_superfamily IPR036892 L27 domain superfamily
Domain Details Per Protein
Protein Length Guanylate kinase, conserved site Guanylate kinase-like domain Guanylate kinase/L-type calcium channel beta subunit L27 domain L27 domain, C-terminal L27 domain superfamily L27-N MPP5, SH3 domain PDZ domain PDZ superfamily P-loop containing nucleoside triphosphate hydrolase SH3 domain SH3-like domain superfamily
UniProtKB:D3X469 639
UniProtKB:A8DZ97 363
UniProtKB:A0A8M3B4D4 512
UniProtKB:A0A8M9PP48 403
UniProtKB:A0A8M3AL41 537
UniProtKB:A0A8M6YU41 377
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA mpp5b-201 (1) Havana 2097 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-pals1b polyclonal Rabbit
  • IHC
  • WB
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations