Gene

camsap1a

ID

ZDB-GENE-060518-4

Name

calmodulin regulated spectrin-associated protein 1a

Symbol

camsap1a Nomenclature History

Previous Names

camsap1

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable microtubule minus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization and negative regulation of microtubule depolymerization. Predicted to act upstream of or within neuron projection development. Predicted to be located in cytoplasm and microtubule. Predicted to colocalize with microtubule minus-end. Orthologous to human CAMSAP1 (calmodulin regulated spectrin associated protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With camsap1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Cortical dysplasia, complex, with other brain malformations 12	620316

Associated With camsap1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR031372	CAMSAP, spectrin and Ca2+/calmodulin-binding region
Domain	IPR001715	Calponin homology domain
Domain	IPR014797	CKK domain
Domain	IPR022613	Calmodulin-regulated spectrin-associated protein-like, Calponin-homology domain
Family	IPR032940	Calmodulin-regulated spectrin-associated protein
Homologous_superfamily	IPR011033	PRC-barrel-like superfamily
Homologous_superfamily	IPR036872	CH domain superfamily
Homologous_superfamily	IPR038209	CKK domain superfamily

Domain Details Per Protein

Protein	Length	Calmodulin-regulated spectrin-associated protein	Calmodulin-regulated spectrin-associated protein-like, Calponin-homology domain	Calponin homology domain	CAMSAP, spectrin and Ca2+/calmodulin-binding region	CH domain superfamily	CKK domain	CKK domain superfamily	PRC-barrel-like superfamily
UniProtKB:A0A8M2B7W8 InterPro	1452
UniProtKB:F1R1D6 InterPro	1458
UniProtKB:A0A8M2B7Y3 InterPro	1441
UniProtKB:A0A8M2B7W9 InterPro	1461

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	camsap1a-201 (1) Ensembl	Ensembl	5,619 nt	Select Tool ZFIN BLAST
mRNA	camsap1a-202 (1) Ensembl	Ensembl	2,748 nt	Select Tool ZFIN BLAST
mRNA	camsap1a-203 (1) Ensembl	Ensembl	4,682 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations