ZFIN is now using GRCz12tu for Genomic Data
Gene
hspa1b
- ID
- ZDB-GENE-060503-867
- Name
- heat shock protein family A (Hsp70) member 1B
- Symbol
- hspa1b Nomenclature History
- Previous Names
-
- si:ch211-199o1.2
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Predicted to be involved in protein refolding. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease of musculoskeletal system (multiple); inner ear disease (multiple); lung disease (multiple); and schizophrenia (multiple). Orthologous to several human genes including HSPA1L (heat shock protein family A (Hsp70) member 1 like); HSPA1A (heat shock protein family A (Hsp70) member 1A); and HSPA1B (heat shock protein family A (Hsp70) member 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from Xiao et al., 2025
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018181 | Heat shock protein 70, conserved site |
| Family | IPR013126 | Heat shock protein 70 family |
| Homologous_superfamily | IPR029047 | Heat shock protein 70kD, peptide-binding domain superfamily |
| Homologous_superfamily | IPR029048 | Heat shock protein 70kD, C-terminal domain superfamily |
| Homologous_superfamily | IPR043129 | ATPase, nucleotide binding domain |
Domain Details Per Protein
| Protein | Additional Resources | Length | ATPase, nucleotide binding domain | Heat shock protein 70, conserved site | Heat shock protein 70 family | Heat shock protein 70kD, C-terminal domain superfamily | Heat shock protein 70kD, peptide-binding domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1NE33 | InterPro | 639 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-199o1.2-201
(1)
|
Ensembl | 2,020 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers