Gene

anln2

ID

ZDB-GENE-060503-826

Name

anillin, actin binding protein 2

Symbol

anln2 Nomenclature History

Previous Names

si:dkey-238c7.5
si:dkey-30c15.10 (1)
si:dkey-30c15.9

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have GTP-Rho binding activity. Predicted to be involved in actomyosin contractile ring assembly; protein localization to mitotic actomyosin contractile ring; and septin ring organization. Predicted to localize to actomyosin contractile ring. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Orthologous to human ANLN (anillin actin binding protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With anln2 Human Ortholog

No data available

Associated With anln2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR012966	Anillin homology domain
Domain	IPR037840	Anillin, PH domain
Homologous_superfamily	IPR011993	PH-like domain superfamily

Domain Details Per Protein

Protein	Length	Anillin homology domain	Anillin, PH domain	PH-like domain superfamily	Pleckstrin homology domain
UniProtKB:A0A0A0MPH2 InterPro
UniProtKB:Q1LX31 InterPro
UniProtKB:A0A8M9PVN7 InterPro	941
UniProtKB:A0A8M9PQM5 InterPro	921
UniProtKB:A0A8M9PFP1 InterPro	938
UniProtKB:A0A8M9Q6T3 InterPro	940
UniProtKB:A0A8M9Q2N4 InterPro	923