Gene
nfatc1
- ID
- ZDB-GENE-060503-677
- Name
- nuclear factor of activated T cells 1
- Symbol
- nfatc1 Nomenclature History
- Previous Names
-
- si:ch211-198c22.2
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within with a negative effect on lymphangiogenesis. Acts upstream of or within atrioventricular valve morphogenesis and response to mechanical stimulus. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including adaxial cell; bone tissue; heart; olfactory system; and scale. Orthologous to human NFATC1 (nuclear factor of activated T cells 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 29 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002909 | IPT domain |
| Domain | IPR011539 | Rel homology domain, DNA-binding domain |
| Domain | IPR032397 | Rel homology dimerisation domain |
| Family | IPR008366 | Nuclear factor of activated T cells (NFAT) |
| Homologous_superfamily | IPR008967 | p53-like transcription factor, DNA-binding domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR037059 | Rel homology domain (RHD), DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin E-set | Immunoglobulin-like fold | IPT domain | Nuclear factor of activated T cells (NFAT) | p53-like transcription factor, DNA-binding domain superfamily | Rel homology dimerisation domain | Rel homology domain, DNA-binding domain | Rel homology domain (RHD), DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q19AW4
|
867 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nfatc1-201
(1)
|
Ensembl | 3,905 nt |
Interactions and Pathways
No data available
Plasmids