Gene

rnf217

ID

ZDB-GENE-060503-400

Name

ring finger protein 217

Symbol

rnf217 Nomenclature History

Previous Names

si:ch211-208c9.4
zgc:174567

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm and ubiquitin ligase complex. Orthologous to human RNF217 (ring finger protein 217).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rnf217 Human Ortholog

No data available

Associated With rnf217 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002867	IBR domain
Domain	IPR044066	TRIAD supradomain
Domain	IPR047550	E3 ubiquitin-protein ligase RNF217, variant RING finger, HC subclass
Domain	IPR047551	E3 ubiquitin-protein ligase RNF217, BRcat domain
Domain	IPR047552	E3 ubiquitin-protein ligase RNF217, Rcat domain
Family	IPR031127	E3 ubiquitin ligase RBR family
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type

Domain Details Per Protein

Protein	Length	E3 ubiquitin ligase RBR family	E3 ubiquitin-protein ligase RNF217, BRcat domain	E3 ubiquitin-protein ligase RNF217, Rcat domain	E3 ubiquitin-protein ligase RNF217, variant RING finger, HC subclass	IBR domain	TRIAD supradomain	Zinc finger, RING/FYVE/PHD-type
UniProtKB:Q1LUI6 InterPro	543

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rnf217-201 (1) Ensembl	Ensembl	2,232 nt	Select Tool ZFIN BLAST
mRNA	rnf217-202 (1) Ensembl	Ensembl	1,912 nt	Select Tool ZFIN BLAST
mRNA	rnf217-203 (1) Ensembl	Ensembl	2,505 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations