Gene

kcnh8

ID

ZDB-GENE-060503-204

Name

potassium voltage-gated channel, subfamily H (eag-related), member 8

Symbol

kcnh8 Nomenclature History

Previous Names

si:ch211-195k18.3 (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport and regulation of membrane potential. Predicted to localize to integral component of plasma membrane. Is expressed in ovary and testis. Orthologous to human KCNH8 (potassium voltage-gated channel subfamily H member 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Kok et al., 2012

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnh8 Human Ortholog

No data available

Associated With kcnh8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR000595	Cyclic nucleotide-binding domain
Domain	IPR000700	PAS-associated, C-terminal
Domain	IPR005821	Ion transport domain
Family	IPR003938	Potassium channel, voltage-dependent, EAG/ELK/ERG
Family	IPR003950	Potassium channel, voltage-dependent, ELK
Homologous_superfamily	IPR014710	RmlC-like jelly roll fold
Homologous_superfamily	IPR018490	Cyclic nucleotide-binding domain superfamily
Homologous_superfamily	IPR035965	PAS domain superfamily
Repeat	IPR001610	PAC motif

Domain Details Per Protein

Protein	Length	Cyclic nucleotide-binding domain	Cyclic nucleotide-binding domain superfamily	Ion transport domain	PAC motif	PAS-associated, C-terminal	PAS domain	PAS domain superfamily	Potassium channel, voltage-dependent, EAG/ELK/ERG	Potassium channel, voltage-dependent, ELK	RmlC-like jelly roll fold
UniProtKB:A0A8M6Z362 InterPro	975

Transcripts

Genome Browsers

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	kcnh8-201 (1) Ensembl	Havana	3707 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations