Gene
ifng1r
- ID
- ZDB-GENE-060210-1
- Name
- interferon gamma related
- Symbol
- ifng1r Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have interferon-gamma receptor binding activity. Involved in defense response to Gram-negative bacterium and immune response. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in several diseases, including ataxia telangiectasia; autoimmune hypersensitivity disease (multiple); bone disease (multiple); eczema herpeticum; and leukemia (multiple). Is expressed in gill and ventral wall of dorsal aorta. Orthologous to human IFNG (interferon gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Sieger et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| aplastic anemia | Alliance | {Aplastic anemia} | 609135 |
| immunodeficiency 69 | Alliance | ?Immunodeficiency 69, mycobacteriosis | 618963 |
| tuberous sclerosis 2 | Alliance | {TSC2 angiomyolipomas, renal, modifier of} | 613254 |
| {AIDS, rapid progression to} | 609423 | ||
| {Hepatitis C virus, response to therapy of} | 609532 | ||
| {Tuberculosis, protection against} | 607948 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Four-helical cytokine-like, core | Interferon gamma |
|---|---|---|---|
|
UniProtKB:Q5TLE6
|
170 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ifng1r-201
(1)
|
Ensembl | 513 nt |
Interactions and Pathways
No data available
Plasmids
No data available