Gene

ogt.2

ID

ZDB-GENE-051128-1

Name

O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2

Symbol

ogt.2 Nomenclature History

Previous Names

ogtb (1)
ogtl
copy II (1)
im:7146393
wu:fp46c04
wu:fr75f09

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Exhibits protein N-acetylglucosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Human ortholog(s) of this gene implicated in X-linked mental retardation 106. Orthologous to human OGT (O-linked N-acetylglucosamine (GlcNAc) transferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7138603 (1 image)
IMAGE:7146393 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Webster et al., 2009
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ogt.2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
non-syndromic X-linked intellectual disability 106	Alliance	Intellectual developmental disorder, X-linked 106	300997

Associated With ogt.2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR029489	O-GlcNAc transferase, C-terminal
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Repeat	IPR019734	Tetratricopeptide repeat

Domain Details Per Protein

Protein	Length	O-GlcNAc transferase, C-terminal	Tetratricopeptide-like helical domain superfamily	Tetratricopeptide repeat
UniProtKB:A0A8M9QPC9 InterPro	870
UniProtKB:A0A8M2B3B2 InterPro	1092
UniProtKB:A0A0R4IVJ0 InterPro	1102

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ogt.1-201 (1) Ensembl	Ensembl	3,111 nt	Select Tool ZFIN BLAST
mRNA	ogt.1-202 (1) Ensembl	Ensembl	3,141 nt	Select Tool ZFIN BLAST
mRNA	ogt.1-204 (1) Ensembl	Ensembl	3,890 nt	Select Tool ZFIN BLAST
ncRNA	ogt.2-002 (1) Ensembl	Ensembl	897 nt	Select Tool ZFIN BLAST
ncRNA	ogt.2-003 (1) Ensembl	Ensembl	761 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations