Gene

primpol

ID
ZDB-GENE-051113-100
Name
primase and polymerase (DNA-directed)
Symbol
primpol Nomenclature History
Previous Names
  • zgc:123274
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have DNA primase activity; DNA-directed DNA polymerase activity; and chromatin binding activity. Predicted to be involved in cellular macromolecule biosynthetic process and response to UV. Predicted to localize to mitochondrial matrix and nucleus. Human ortholog(s) of this gene implicated in myopia. Orthologous to human PRIMPOL (primase and DNA directed polymerase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Chen et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With primpol Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
myopia Alliance Myopia 22, autosomal dominant 615420
Associated With primpol Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR044917 DNA-directed primase/polymerase protein
Domain Details Per Protein
Protein Length DNA-directed primase/polymerase protein
UniProtKB:Q32PL8 523
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations