Gene

nde1

ID
ZDB-GENE-050913-61
Name
nudE neurodevelopment protein 1
Symbol
nde1 Nomenclature History
Previous Names
  • fb82g01
  • im:7141877
  • wu:fb82g01
  • zgc:114109
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have microtubule binding activity. Involved in regulation of cell projection size. Predicted to localize to centrosome; kinesin complex; and kinetochore. Human ortholog(s) of this gene implicated in lissencephaly. Orthologous to human NDE1 (nudE neurodevelopment protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Kim et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nde1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
lissencephaly 4 Alliance Lissencephaly 4 (with microcephaly) 614019
Microhydranencephaly 605013
Associated With nde1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006964 NUDE domain
Family IPR033494 NUDE family
Domain Details Per Protein
Protein Length NUDE domain NUDE family
UniProtKB:Q4V8W6 336
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations