Gene
pacsin1b
- ID
- ZDB-GENE-050913-35
- Name
- protein kinase C and casein kinase substrate in neurons 1b
- Symbol
- pacsin1b Nomenclature History
- Previous Names
-
- pacsin1
- fe25d06
- syndapin I (1)
- wu:fe25d06
- zgc:114042
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have cytoskeletal protein binding activity and phospholipid binding activity. Involved in auditory receptor cell stereocilium organization and cilium assembly. Predicted to localize to cytoskeleton; endosome; and plasma membrane. Is expressed in nervous system; post-vent region; presumptive neural retina; and trunk. Orthologous to human PACSIN1 (protein kinase C and casein kinase substrate in neurons 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001060 | FCH domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR031160 | F-BAR domain |
| Domain | IPR035743 | PACSIN1/PACSIN2, SH3 domain |
| Domain | IPR037454 | PACSIN1, F-BAR |
| Homologous_superfamily | IPR027267 | AH/BAR domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | F-BAR domain | FCH domain | PACSIN1, F-BAR | PACSIN1/PACSIN2, SH3 domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B2GTA5
|
445 | |||||||
|
UniProtKB:Q4V920
|
445 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
pacsin1b-201
(1)
|
Havana | 2622 nt | |
| mRNA |
pacsin1b-202
(1)
|
Havana | 2663 nt | |
| mRNA |
pacsin1b-203
(1)
|
Havana | 561 nt |
Interactions and Pathways
No data available
Plasmids
No data available