Gene

igsf21a

ID

ZDB-GENE-050809-118

Name

immunoglobin superfamily, member 21a

Symbol

igsf21a Nomenclature History

Previous Names

zgc:112341

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have cell adhesion molecule binding activity; protein homodimerization activity; and signaling receptor activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to localize to adherens junction. Is expressed in brain; pectoral fin musculature; and retina. Orthologous to human IGSF21 (immunoglobin superfamily member 21).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d0751 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With igsf21a Human Ortholog

No data available

Associated With igsf21a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003006	Immunoglobulin/major histocompatibility complex, conserved site
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR051427	Nectin and Nectin-like
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	Immunoglobulin domain subtype	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin/major histocompatibility complex, conserved site	Immunoglobulin V-set domain	Nectin and Nectin-like
UniProtKB:A0A8M1N7V4 InterPro	475
UniProtKB:Q498W1 InterPro	472
UniProtKB:F1QR24 InterPro	470

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	igsf21a-201 (1) Ensembl	Ensembl	3,198 nt	Select Tool
mRNA	igsf21a-202 (1) Ensembl	Ensembl	2,235 nt	Select Tool ZFIN BLAST
mRNA	igsf21a-203 (1) Ensembl	Ensembl	836 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-igsf21a	monoclonal	igsf21a		Mouse	IHC		1

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations