Gene
pcdh1g1
- ID
- ZDB-GENE-050608-1
- Name
- protocadherin 1 gamma 1
- Symbol
- pcdh1g1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain. Orthologous to several human genes including PCDHB11 (protocadherin beta 11); PCDHB12 (protocadherin beta 12); and PCDHB13 (protocadherin beta 13).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cadherin conserved site | Cadherin, C-terminal catenin-binding domain | Cadherin, cytoplasmic C-terminal domain | Cadherin-like | Cadherin-like superfamily | Cadherin, N-terminal | Protocadherin/Cadherin-related Cell Adhesion |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:I6LC07
|
932 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pcdh1g1-201
(1)
|
Ensembl | 4,335 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-17C10 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-179G5 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-263M6 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001020804 (1) | 4338 nt | ||
| Genomic | GenBank:AC144828 (1) | 187958 nt | ||
| Polypeptide | UniProtKB:I6LC07 (1) | 932 aa |
No data available
- Barthelson, K., Baer, L., Dong, Y., Hand, M., Pujic, Z., Newman, M., Goodhill, G.J., Richards, R.I., Pederson, S.M., Lardelli, M. (2021) Zebrafish Chromosome 14 Gene Differential Expression in the fmr1hu2787 Model of Fragile X Syndrome. Frontiers in genetics. 12:625466
- Tsai, T.Y., Sikora, M., Xia, P., Colak-Champollion, T., Knaut, H., Heisenberg, C.P., Megason, S.G. (2020) An adhesion code ensures robust pattern formation during tissue morphogenesis. Science (New York, N.Y.). 370:113-116
- Cho, H.J., Lee, J.G., Kim, J.H., Kim, S.Y., Huh, Y.H., Kim, H.J., Lee, K.S., Yu, K., Lee, J.S. (2019) Vascular defects of DYRK1A knockouts are ameliorated by modulating calcium signaling in zebrafish. Disease models & mechanisms. 12(5):
- Tan, Y.P., Li, S., Jiang, X.J., Loh, W., Foo, Y.K., Loh, C.B., Xu, Q., Yuen, W.H., Jones, M., Fu, J., Venkatesh, B., and Yu, W.P. (2010) Regulation of protocadherin gene expression by multiple neuron-restrictive silencer elements scattered in the gene cluster. Nucleic acids research. 38(15):4985-4997
- Wu, Q. (2005) Comparative Genomics and Diversifying Selection of the Clustered Vertebrate Protocadherin Genes. Genetics. 169(4):2179-2188
- Noonan, J.P., Grimwood, J., Schmutz, J., Dickson, M., and Myers, R.M. (2004) Gene conversion and the evolution of protocadherin gene cluster diversity. Genome research. 14(3):354-366
- Tada, M.N., Senzaki, K., Tai, Y., Morishita, H., Tanaka, Y.Z., Murata, Y., Ishii, Y., Asakawa, S., Shimizu, N., Sugino, H., and Yagi, T. (2004) Genomic organization and transcripts of the zebrafish Protocadherin genes. Gene. 340(2):197-211
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