Gene
cyp3a65
- ID
- ZDB-GENE-050604-1
- Name
- cytochrome P450, family 3, subfamily A, polypeptide 65
- Symbol
- cyp3a65 Nomenclature History
- Previous Names
-
- zgc:123110
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable steroid hydroxylase activity. Acts upstream of or within response to xenobiotic stimulus. Predicted to be located in endoplasmic reticulum and membrane. Is expressed in several structures, including digestive system; eye; gill; heart; and ovary. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 33 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome P450 | Cytochrome P450 3A | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q32LT1 | InterPro | 517 | |||||
| UniProtKB:A0A8M1N818 | InterPro | 517 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp3a65-201
(1)
|
Ensembl | 2,020 nt |
Interactions and Pathways
No data available
Plasmids
No data available