Gene
uqcrb
- ID
- ZDB-GENE-050522-542
- Name
- ubiquinol-cytochrome c reductase binding protein
- Symbol
- uqcrb Nomenclature History
- Previous Names
-
- im:6900881
- zgc:109893
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to contribute to ubiquinol-cytochrome-c reductase activity. Involved in angiogenesis. Predicted to localize to mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in inherited metabolic disorder and mitochondrial complex III deficiency nuclear type 3. Is expressed in several structures, including adaxial cell; alar plate midbrain region; digestive system; optic tectum; and pronephric duct. Orthologous to human UQCRB (ubiquinol-cytochrome c reductase binding protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6900881 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Cho et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex III deficiency nuclear type 3 | Alliance | Mitochondrial complex III deficiency, nuclear type 3 | 615158 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome b-c1 complex subunit 7 | Cytochrome b-c1 complex subunit 7 superfamily |
|---|---|---|---|
|
UniProtKB:Q4VBV1
|
111 |
Interactions and Pathways
No data available
Plasmids
No data available