Gene

eri1

ID
ZDB-GENE-050522-39
Name
exoribonuclease 1
Symbol
eri1 Nomenclature History
Previous Names
  • MGC35395 (1)
  • thex1
  • zgc:110635
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have 3'-5'-exoribonuclease activity. Predicted to be involved in DNA catabolic process, exonucleolytic and exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to localize to cytoplasm and nucleolus. Orthologous to human ERI1 (exoribonuclease 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eri1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hoxha-Aliu syndrome 620662
Spondyloepimetaphyseal dysplasia, Guo-Campeau type 620663
Associated With eri1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003034 SAP domain
Domain IPR013520 Exonuclease, RNase T/DNA polymerase III
Domain IPR047201 ERI-1-like, DEDDh 3'-5' exonuclease domain
Homologous_superfamily IPR012337 Ribonuclease H-like superfamily
Homologous_superfamily IPR036361 SAP domain superfamily
Homologous_superfamily IPR036397 Ribonuclease H superfamily
Domain Details Per Protein
Protein Length ERI-1-like, DEDDh 3'-5' exonuclease domain Exonuclease, RNase T/DNA polymerase III Ribonuclease H-like superfamily Ribonuclease H superfamily SAP domain SAP domain superfamily
UniProtKB:Q503G0 337
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations