Gene

rras2

ID
ZDB-GENE-050417-352
Name
RAS related 2
Symbol
rras2 Nomenclature History
Previous Names
  • wu:fc47b08
  • zgc:110215
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Ras protein signal transduction. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome. Is expressed in several structures, including adaxial cell; head mesenchyme; hindbrain neural plate; musculature system; and notochord. Orthologous to human RRAS2 (RAS related 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rras2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Noonan syndrome 12 Alliance Noonan syndrome 12 618624
Ovarian carcinoma
Associated With rras2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005225 Small GTP-binding protein domain
Family IPR001806 Small GTPase
Family IPR020849 Small GTPase, Ras-type
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTPase, Ras-type Small GTP-binding protein domain
UniProtKB:Q568M0 202
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations