ZFIN is now using GRCz12tu for Genomic Data
Gene
klc4
- ID
- ZDB-GENE-050417-350
- Name
- kinesin light chain 4
- Symbol
- klc4 Nomenclature History
- Previous Names
-
- zgc:110314
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be located in cytoplasm. Predicted to be part of kinesin complex. Is expressed in nervous system. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human KLC4 (kinesin light chain 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Haynes et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from Haynes et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| early-childhood-onset neurodegeneration with retinitis pigmentosa, sensorineural hearing loss, and demyelinating peripheral neuropathy | Alliance | ?Neurodegeneration, early-childhood-onset, with retinitis pigmentosa, sensorineural hearing loss, and demyelinating peripheral neuropathy | 621129 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR002151 | Kinesin light chain |
Domain Details Per Protein
| Protein | Additional Resources | Length | Kinesin light chain |
|---|---|---|---|
| UniProtKB:Q568G6 | InterPro | 185 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers