ZFIN is now using GRCz12tu for Genomic Data
Gene
mrpl12
- ID
- ZDB-GENE-050417-187
- Name
- mitochondrial ribosomal protein L12
- Symbol
- mrpl12 Nomenclature History
- Previous Names
-
- im:6893415
- zgc:112445
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrial inner membrane; mitochondrial matrix; and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; optic vesicle; and pectoral fin. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 45. Orthologous to human MRPL12 (mitochondrial ribosomal protein L12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6893415 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 45 | Alliance | ?Combined oxidative phosphorylation deficiency 45 | 618951 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR008932 | Large ribosomal subunit protein bL12, oligomerization |
| Domain | IPR013823 | Large ribosomal subunit protein bL12, C-terminal |
| Family | IPR000206 | Large ribosomal subunit protein bL12 |
| Homologous_superfamily | IPR014719 | Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like |
| Homologous_superfamily | IPR036235 | Large ribosomal subunit protein bL12, oligomerization domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Large ribosomal subunit protein bL12 | Large ribosomal subunit protein bL12, C-terminal | Large ribosomal subunit protein bL12, oligomerization | Large ribosomal subunit protein bL12, oligomerization domain superfamily | Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q566V8 | InterPro | 194 | |||||
| UniProtKB:X1WHQ5 | InterPro | 199 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mrpl12-201
(1)
|
Ensembl | 1,057 nt | ||
| mRNA |
mrpl12-202
(1)
|
Ensembl | 1,287 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers